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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
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Commonly Used Dietary Supplements on Coagulation Function during Surgery.

Chong-Zhi Wang1, Jonathan Moss1, Chun-Su Yuan1

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Summary
This summary is machine-generated.

Patients often use dietary supplements, which can increase bleeding risks during surgery. Physicians should be aware of these risks and advise patients to stop supplements before procedures.

Keywords:
bleedingcoagulationdietary supplementsnatural productsplatelet functionsurgery

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Area of Science:

  • Pharmacology
  • Integrative Medicine
  • Surgical Care

Background:

  • Patients undergoing surgery frequently use dietary supplements.
  • Dietary supplements contain active compounds that can affect perioperative coagulation and platelet function.
  • Limited research exists on the pharmacological interactions of dietary supplements in surgical patients.

Purpose of the Study:

  • To systematically review the effects of commonly used dietary supplements on blood coagulation and platelet function.
  • To identify potential bleeding risks and drug interactions associated with dietary supplements in the perioperative period.

Main Methods:

  • Systematic database search for articles on dietary supplements and coagulation/platelet function.
  • Focus on studies published after 1990.
  • Review of 11 herbal medicines and 4 other dietary supplements.

Main Results:

  • Commonly used supplements like garlic, ginkgo, ginseng, green tea, saw palmetto, St. John's wort, and fish oil are associated with bleeding risks.
  • Ephedra, ginseng, and kava can cause cardiovascular instability.
  • Pharmacodynamic and pharmacokinetic interactions between supplements and perioperative drugs are discussed.

Conclusions:

  • Physicians need to understand the perioperative effects of popular dietary supplements.
  • Due to unpredictable effects on coagulation, discontinuing supplements before surgery is advisable to prevent complications.