Is there any relation between Duration of breastfeeding and anemia?

H Dalili1, A Baghersalimi2, S Dalili3

  • 1Department of Pediatrics, Breastfeeding Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Insights

Exclusive breastfeeding for over six months increases anemia risk in infants. However, breastfeeding for four months significantly reduces this risk. Health programs should consider iron supplementation and delivery practices.

Area of Science:

  • Pediatrics
  • Public Health
  • Nutrition

Background:

  • Breastfeeding is crucial for infant survival, reducing disease recovery time and mortality from infections.
  • Prolonged exclusive breastfeeding (over 6 months) in developing nations is linked to increased infant anemia risk.
  • This study investigates the relationship between breastfeeding duration and anemia in neonates.

Purpose of the Study:

  • To assess the association between the duration of breastfeeding and the incidence of anemia in infants.
  • To identify factors influencing anemia in neonates within a primary healthcare setting.

Main Methods:

  • An analytical cross-sectional study involving 400 neonates.
  • Collected data included complete blood count and serum ferritin levels.
  • Statistical analysis employed chi-square and regression analyses, with significance set at P<0.05.

Main Results:

  • 199 infants (49.75%) were identified as anemic (Hemoglobin <11 mg/dL).
  • Iron deficiency anemia (IDA) was present in 25% of anemic infants; 10% had low ferritin (<12 ng/dL).
  • Logistic regression indicated that delivery type and breastfeeding duration were significant factors; exclusive breastfeeding for 6+ months increased anemia likelihood, while 4 months of exclusive breastfeeding reduced it by 0.686 fold.

Conclusions:

  • Current health program recommendations for iron supplementation may require revision.
  • National strategies should focus on educating about natural vaginal delivery and optimal umbilical cord clamping timing.
  • Findings suggest a critical window for exclusive breastfeeding duration to mitigate anemia risk.
Abstract

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1.1K
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
11
Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship01:14

Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship

For drugs producing a quantal response, onset occurs when plasma concentration reaches a minimum effective level (Cmin). The drug's action duration depends on how long the plasma concentration remains above Cmin.Two primary factors influence this duration: dose size and the rate of drug removal from the action site. Both depend on the drug's redistribution to poorly perfused tissues and elimination processes. A larger dose promotes rapid onset and prolongs the effect's duration.Consider a...
84
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
678
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
4.1K
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
10