Retinal Pigment Epithelium Hyperplasia After Unsuccessful Surgery for Macular Hole

An 81-year-old woman presented with a retinal tumor after unsuccessful surgery was performed for a macular hole (MH) in the 1990s. A histopathological analysis revealed retinal pigment epithelium hyperplasia with no evidence of neoplastic cells. This case highlights two points: first, MHs that remain open after unsuccessful MH surgery can cause retinal tumors, leading to further visual loss; and second, in this case, the MH-associated tumor showed no evidence of neoplastic cells.