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Related Experiment Video

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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography.

J Howlett1, K Vahdani1, J Rossiter1

  • 1Department of Ophthalmology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom.

Journal of Current Glaucoma Practice
|March 22, 2016
PubMed
Summary
This summary is machine-generated.

Bulbar conjunctival and Tenon's layer thickness varies significantly between individuals, impacting glaucoma surgery outcomes. Optical coherence tomography (OCT) can measure these layers to predict bleb function and guide treatment.

Keywords:
Bulbar conjunc tival thicknessOptical coherence tomography.Tenon's layer thickne ss

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Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Ophthalmic Imaging

Background:

  • Variability in bulbar conjunctiva and Tenon's layers thickness observed during glaucoma surgery.
  • Potential influence of these tissue layers on the morphology and function of filtration blebs.

Purpose of the Study:

  • To pilot a study assessing bulbar conjunctival and Tenon's layer thickness.
  • Utilize optical coherence tomography (OCT) for precise measurements.
  • Correlate tissue thickness with potential bleb outcomes.

Main Methods:

  • Pilot study involving 67 eyes from 48 individuals.
  • Optical coherence tomography (OCT) (Optovue Mode RT100) used for imaging.
  • Combined bulbar conjunctival and Tenon's layer thickness measured 3 mm superior to the limbus.

Main Results:

  • Mean combined thickness was 393 ± 67 microns (range: 194–573 microns).
  • Significant inter-individual variation in thickness was observed.
  • Patient demographics: age 23–91 years, 20 males, 28 females.

Conclusions:

  • OCT measurements reveal substantial variation in conjunctival and Tenon's layer thickness.
  • This variability may predict bleb encapsulation, failure, or thin avascular blebs.
  • Further research could establish cut-offs for intraoperative interventions like antimetabolites or Tenon's excision.