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Updated: Mar 23, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
[Multidisciplinary and cross-sectorial treatment of patients with complex regional pain syndrome]
Lene Møller Schear Mikkelsen1, Hanne Tønnesen, Per Rotbøll Nielsen
1lene.moeller.schear.mikkelsen@regionh.dk.
Abstract:
Complex regional pain syndrome (CRPS) is a complex, painful, debilitating disease which occurs after trauma or surgery mainly in the wrists with a variation of 5.5-26.2 at 100,000 inhabitants in international studies. In Denmark the prevalence is unknown, and it is perceived that many patients with CRPS are diagnosed late in their illness. There is international consensus on diagnostic criteria and early identification. Evidence for treatment is weak, but there are good experiences with highly specialized multidisciplinary treatment. A national clinical guideline is required.
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