Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
Allergic Reactions02:06

Allergic Reactions

33.4K
Overview
33.4K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

142
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
142
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.7K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.7K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.8K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.8K
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

983
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
983

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The age of eczema onset and multiple food allergies.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2025
Same author

Psychobiologic Correlates of Stress in Individuals With COPD.

Chronic obstructive pulmonary diseases (Miami, Fla.)·2025
Same author

Food allergy perceptions among youth with food allergy and their caregivers.

The journal of allergy and clinical immunology. In practice·2023
Same author

Rates of New Peanut Allergy and Discontinuation Following Introduction in High-Risk Infants.

The journal of allergy and clinical immunology. In practice·2023
Same author

Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy.

The New England journal of medicine·2023
Same author

Accelerating Food Allergy Research: Need for a Data Commons.

The journal of allergy and clinical immunology. In practice·2023
Same journal

Anaphylaxis: State-of-the-Art.

Immunology and allergy clinics of North America·2026
Same journal

Upending Impending Doom.

Immunology and allergy clinics of North America·2026
Same journal

Mast Cell Activation Syndrome and Mimickers.

Immunology and allergy clinics of North America·2026
Same journal

Hereditary Alpha-Tryptasemia (HαT) as a Risk Modifier for Severe Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Emerging Therapies for Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Novel Epinephrine Delivery Devices.

Immunology and allergy clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K

Allergic Rhinitis: Environmental Determinants.

Joan Dunlop1, Elizabeth Matsui2, Hemant P Sharma3

  • 1Division of Emergency Medicine, Children's National Health System, 111 Michigan Avenue NW, Washington, DC 20010, USA.

Immunology and Allergy Clinics of North America
|April 17, 2016
PubMed
Summary
This summary is machine-generated.

Environmental factors significantly impact allergic rhinitis (AR) risk, interacting with genetics. Key triggers include aeroallergens, air pollution, and toxicants, contributing to rising AR prevalence worldwide.

Keywords:
AllergenAllergic rhinitisEnvironmentRiskSensitization

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.6K

Related Experiment Videos

Last Updated: Mar 22, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.6K

Area of Science:

  • Immunology
  • Environmental Health
  • Genetics

Background:

  • Allergic rhinitis (AR) prevalence is increasing globally.
  • Genetic predisposition plays a role in AR development.
  • Environmental factors are suspected contributors to AR's rise.

Purpose of the Study:

  • To examine environmental determinants of allergic rhinitis.
  • To review evidence linking environmental factors to AR prevalence.
  • To understand the interplay between environment, genetics, and AR.

Main Methods:

  • Literature review of environmental exposures and AR.
  • Analysis of epidemiological data on AR prevalence.
  • Examination of pathogenetic mechanisms of AR.

Main Results:

  • Aeroallergen exposure is strongly linked to AR development and progression.
  • Air pollution, bacterial exposure, and toxicants are potential risk factors for AR.
  • Environmental factors interact with genetic predisposition to influence AR risk.

Conclusions:

  • Environmental factors are critical in the increasing prevalence of allergic rhinitis.
  • Understanding these environmental triggers is key to managing and preventing AR.
  • Further research into the specific roles of various environmental exposures is warranted.