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Updated: Mar 22, 2026

CD Spectroscopy to Study DNA-Protein Interactions
Published on: February 10, 2022
Spectral-Statistical Approach for Revealing Latent Regular Structures in DNA Sequence
Maria Chaley1, Vladimir Kutyrkin2
1Institute of Mathematical Problems of Biology, Russian Academy of Sciences, Institutskaya st., 4, 142290, Pushchino, Russia. maramaria@yandex.ru.
Abstract:
Methods of the spectral-statistical approach (2S-approach) for revealing latent periodicity in DNA sequences are described. The results of data analysis in the HeteroGenome database which collects the sequences similar to approximate tandem repeats in the genomes of model organisms are adduced. In consequence of further developing of the spectral-statistical approach, the techniques for recognizing latent profile periodicity are considered. These techniques are basing on extension of the notion of approximate tandem repeat. Examples of correlation of latent profile periodicity revealed in the CDSs with structural-functional properties in the proteins are given.
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