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Updated: Mar 21, 2026

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Published on: October 26, 2017
Analysis of Plasma microRNA Associated with Hemolysis
M Yu Shkurnikov1,2, E N Knyazev3, K A Fomicheva4
1BioClinicum Research and Development Center, Moscow, Russia. mshkurnikov@imscs.msu.ru.
Abstract:
We analyzed the effect of hemolysis on microRNA profi le of blood plasma. It was found that hemolysis of ~0.05% erythrocytes in a sample signifi cantly affected the concentration of 9 microRNA: hsa-miR-486-5p, hsa-miR-16-5p, hsa-miR-451a, hsa-miR-106a-5p, hsa-miR-17-5p, hsa-miR-93-5p, hsa-miR-20a-5p, hsa-miR-107, and hsa-miR-20b-5p. The effect of hemolysis on plasma content of miR-17 family microRNA was demonstrated.
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