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Outcomes of Concomitant Total Aortic Arch Replacement with Coronary Artery Bypass Grafting
Ken Yamanaka1, Tatsuhiko Komiya, Hiroshi Tsuneyoshi
1Department of Cardiovascular Surgery, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Insights
Total aortic arch replacement can be safely combined with coronary artery bypass grafting. This combined surgery does not increase mortality risk, making it a viable option for suitable patients.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Total aortic arch replacement is a complex and invasive surgical procedure.
- Concomitant coronary artery bypass grafting may be considered in patients undergoing aortic arch repair.
Purpose of the Study:
- To investigate patient outcomes comparing total aortic arch replacement with and without coronary artery bypass grafting.
- To identify factors influencing long-term mortality in patients undergoing total aortic arch replacement.
Main Methods:
- Retrospective analysis of 246 patients: 181 (total aortic arch replacement alone) and 65 (total aortic arch replacement with coronary artery bypass grafting).
- Comparison of preoperative, operative, and postoperative factors.
- Univariate and multivariate analyses to assess survival outcomes and identify mortality risk factors.
Main Results:
- Longer cardiopulmonary bypass and surgical times were observed in the combined surgery group.
- Hospital mortality rates were 3.3% (total aortic arch replacement) and 7.7% (combined surgery), with no statistically significant difference.
- Multivariate analysis identified age, ischemic heart disease, and eGFR as mortality risk factors, but not concomitant coronary artery bypass grafting.
Conclusions:
- Total aortic arch replacement can be performed concomitantly with coronary artery bypass grafting without increasing mortality risk.
- Patient-specific factors, such as age and comorbidities, are crucial in determining long-term outcomes.
Objective:
Total aortic arch replacement is a highly invasive procedure. Here, we have investigated patient outcomes following total aortic arch replacement with or without coronary artery bypass grafting.
Methods:
One hundred and eighty-one patients underwent total aortic arch replacement without coronary artery bypass grafting, and 65 underwent with coronary artery bypass grafting. We compared preoperative, operative, and postoperative factors and analyzed survival outcomes. We used univariate and multivariate analyses to determine factors associated with long-term mortality.
Results:
Cardiopulmonary bypass and surgical times were significantly longer in the concomitant total aortic arch replacement with coronary artery bypass grafting group. Hospital mortality was 3.3% in the total aortic arch replacement group and 7.7% in the concomitant total aortic arch replacement with coronary artery bypass grafting group. Perioperative myocardial infarction was not seen in either group. There were no significant differences in mortality between the groups. Multivariate analysis revealed preoperative age, ischemic heart disease, and estimated glemerular filtration rate (eGFR) as risk factors affecting long-term mortality, whereas concomitant total aortic arch replacement with coronary artery bypass grafting was not a risk factor.
Conclusion:
Although patients' backgrounds should be considered, total aortic arch replacement can be concomitantly performed with coronary artery bypass grafting surgery without additional mortality risk.
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