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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
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Amelanotic Irido-Ciliary Ring Melanoma: A Clinicopathological Correlation
Hassan A Aziz1, Yasha S Modi1, Thomas P Plesec2
1Department of Ophthalmology, Cole Eye Institute, Cleveland, Ohio, USA.
Purpose:
To report a case of an amelanotic irido-ciliary ring melanoma.
Design:
Interventional case report.
Results:
A 44-year-old male was followed for asymptomatic amelanotic iris nevus of the right eye that was noted to have a localized ciliary body mass with ring extension along the trabecular meshwork. Fine needle aspiration biopsy was consistent with malignant melanoma. The patient underwent enucleation and remains disease free at 9 years of follow-up. Histopathology revealed malignant melanoma involving the iris and ciliary body with a 360-degree extension along the trabecular meshwork. The tumor was composed of a mixture of spindled and epithelioid cells with scant pigmentation.
Conclusions:
Amelanotic irido-ciliary ring melanoma with growth along the trabecular meshwork is a rare form of uveal melanoma that could present as an inconspicuous amelanotic iris mass.
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