Direct analysis in real time-Mass spectrometry (DART-MS) in forensic and security applications

Area of Science:

• Forensic Science
• Analytical Chemistry
• Mass Spectrometry

Background:

• Direct Analysis in Real Time (DART) is an ambient ionization technique.
• DART enables rapid analysis of diverse chemical samples with minimal preparation.
• Its utility in forensic science has grown significantly over the past decade.

Purpose of the Study:

• To review and summarize the diverse forensic applications of DART.
• To provide forensic scientists with a resource for developing DART applications.
• To expand upon existing literature, focusing beyond drug analysis.

Main Methods:

• Review of existing literature on DART applications in forensics.
• Categorization of applications including trace evidence, security, and materials analysis.
• Discussion of experimental and data analysis methodologies.

Main Results:

• DART is effective for analyzing seized drugs, explosives, toxic chemicals, and adulterated products.
• Applications extend to chemical warfare agents, inks, dyes, and biological materials.
• The technique is valuable for trace evidence and security screening.

Conclusions:

• DART is a versatile and powerful tool for a wide array of forensic investigations.
• Its ease of use and minimal sample preparation make it ideal for field applications.
• This review serves as a comprehensive guide for forensic scientists utilizing DART technology.