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Updated: Mar 18, 2026

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes
Published on: April 12, 2015
Stem cells: to be born great, achieve greatness, or have greatness thrust upon them?
Raymond Tran1, Corinne A Hoesli1, Christopher Moraes1
1Department of Chemical Engineering, McGill University, Canada. chris.moraes@mcgill.ca.
Abstract:
Induced pluripotent stem cells (iPSCs) have opened new doors in providing an ethical, patient-specific cell source towards tissue engineering. Developing these therapies involves the production of reprogrammed iPSCs, expanding them while maintaining pluripotency, then differentiating them into functional tissues. To bring these therapies to the clinic, efficient and GMP-compliant manufacturing methods are required. In this Research Highlight, we describe recent innovations to several aspects of the pluripotent cell therapy pipeline.
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