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Updated: Mar 18, 2026

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase
Published on: April 4, 2025
Leishmaniasis with Femoral Bone Involvement
Payman Sasannejad1, Mostafa Mazloum Farsi Baf2, Naghmeh Zabolinejad3
1Department of Orthopedics, Islamic Azad University, Medical Branch, Mashhad, Iran.
Abstract:
Visceral leishmaniasis is mostly subclinical, but it can become symptomatic and take acute, subacute or chronic forms. Its incubation period varies from weeks to months and can even be as long as years. Avast variety of organ involvement may be there. We report a case of osseous leishmaniasis presenting with only a long standing mild knee pain without any laboratory or organ abnormality and showed a pure bone involvement on X-ray and CTscan. Later on, it developed into a discharging sinus and the discharge showed Leishman bodies which was reconfirmed the rough bite. As the patient had reactions with amphotericin B, systemic glucantine was given which led to clinical improvement and smaller radiological lesion.
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