Related Experiment Video
Updated: Mar 18, 2026
10:34
An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
Published on: August 7, 2013
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Enteric neuropathies: Yesterday, Today and Tomorrow
Roberto De Giorgio1,2, Francesca Bianco3,4, Rocco Latorre3,5
1Department of Medical and Surgical Sciences, University of Bologna, St. Orsola-Malpighi Hospital, Via Massarenti 9, Bologna, Italy. roberto.degiorgio@unibo.it.
Advances in Experimental Medicine and Biology
|July 6, 2016
Summary
Enteric neuropathies impair gastrointestinal innervation, leading to severe digestive diseases. This review explores historical, current, and future knowledge of these complex conditions.
Area of Science:
- Gastroenterology
- Neurology
- Digestive Diseases
Background:
- Enteric neuropathy involves impaired gastrointestinal innervation.
- Clinical symptoms represent a fraction of underlying functional digestive disorders.
- Pathogenesis and curative treatments for enteric neuropathies remain challenging.
Purpose of the Study:
- To review advancements in understanding adult enteric neuropathies.
- To provide a historical perspective on key discoveries.
- To outline the current state and future directions in the field.
Main Methods:
- Literature review of enteric neuropathies.
- Historical analysis of pioneering research.
- Synthesis of current knowledge and future outlook.
Main Results:
- Progress has been made in understanding enteric neuropathies.
- Mechanisms remain incompletely understood.
- Therapeutic options are largely supportive.
Conclusions:
- Enteric neuropathies are complex conditions with significant impact.
- Further research is needed to elucidate pathogenesis and develop curative therapies.
- This review provides a comprehensive overview for future research and clinical practice.
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