Synthesis of 4'-C-Ethynyl-β-D-ribo-pentofuranosyl Pyrimidines
R Yamaguchi1, T Imanishi1, S Kohgo1
1a Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University.
Bioscience, Biotechnology, and Biochemistry
|July 9, 2016
Abstract:
The 4'-C-ethynyl-β-D-ribo-pentofuranosylpyrimidines were prepared from D-glucose through properly protected 4'-C-formyl-D-ribo-ribofuranose as the key intermediate, and preliminary biological tests against some viruses and tumor cells showed that the compounds were not active.
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