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Published on: February 4, 2022
Normal Cerebellar Development by Qualitative and Quantitative MR Imaging: From the Fetus to the Adolescent
Marie Brossard-Racine1, Catherine Limperopoulos2
1MRI Research of the Developing Brain, Developing Brain Research Program, Division of Neonatology, Children's National Medical Center, 1001 Décarie Boulevard, ES1.5066.1 Montréal, QC, H4A3J1 Canada; School of Physical and Occupational Therapy, Department of Pediatrics and Department of Neurology & Neurosurgery, McGill University, Montreal, Canada.
Abstract:
This article presents an overview of published studies using conventional and quantitative MR imaging to describe normal development of the cerebellum prenatally and postnatally through 18 years of age. Normal cerebellar development and maturational processes are described here within the context of MR imaging morphology, microstructure, metabolism, and functional connectivity. In addition, strengths and weaknesses of these reviewed studies are critically appraised and new directions for future cerebellar MR imaging investigation are made.
