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Updated: Mar 17, 2026

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
Published on: September 7, 2017
mRNA methylation by NSUN2 in cell proliferation
1Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, PR China. wwg@bjmu.edu.cn.
Abstract:
Methylation is a prevalent post-transcriptional modification that occurs in almost all RNA species. NSUN2, a nucleolar RNA methyltransferase, has been shown to methylate mRNAs encoding factors that control cell division and growth arrest, thereby affecting their stability and/or translation. Here, the author summarizes the recent progress in understanding NSUN2-mediated mRNA methylation and its implications in cell proliferation and senescence. WIREs RNA 2016, 7:838-842. doi: 10.1002/wrna.1380 For further resources related to this article, please visit the WIREs website.
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