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Updated: Mar 16, 2026

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Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
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Scoliosis in Down's syndrome
Oussama Abousamra1, Maria Del Pilar Duque Orozco, Mehmet S Er
1Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA.
Journal of Pediatric Orthopedics. Part B
|August 23, 2016
Summary
This study on scoliosis in Down syndrome found bracing effective for most patients and posterior spinal fusion successful with minimal complications. Cardiac surgery history did not differ between those with and without scoliosis.
Area of Science:
- Orthopedics
- Genetics
- Pediatrics
Background:
- Scoliosis is a common spinal deformity that can affect individuals with Down syndrome.
- Understanding management outcomes is crucial for this population.
Purpose of the Study:
- To evaluate the management, curve patterns, and outcomes of scoliosis in children with Down syndrome.
- To compare cardiac surgery history in children with and without scoliosis.
Main Methods:
- Retrospective analysis of 62 children with Down syndrome and scoliosis.
- Assessment of bracing success and surgical outcomes (posterior spinal fusion).
- Comparison of cardiac surgery history between groups.
Main Results:
- The mean age was 13.8 years with a mean curve magnitude of 31°.
- Bracing was successful in 5 out of 7 patients.
- Posterior spinal fusion in 10 patients showed one deep wound infection with no revisions. No significant difference in cardiac surgery history was observed.
Conclusions:
- Scoliosis management in Down syndrome, including bracing and surgical fusion, can yield positive outcomes.
- Scoliosis in Down syndrome does not appear to be associated with a higher incidence of cardiac surgery history.
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