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Updated: Jul 10, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

[Myocardial infarct with normal coronary angiogram].

¹Medizinische Klinik A am Städt, Klinikum Wiesbaden.

Zeitschrift Fur Kardiologie

|June 1, 1989

Summary

A woman survived a wine cellar incident where her husband died, but she later experienced a severe myocardial infarction. This suggests a potential link between environmental factors and cardiac events, possibly due to spasm.

Area of Science:

Cardiology
Toxicology
Environmental Medicine

Background:

Fermenting wine cellars can accumulate toxic gases like carbon dioxide.
Exposure to such environments can lead to systemic physiological stress.

Observation:

A 50-year-old woman survived a fatal wine cellar incident, while her husband succumbed.
She subsequently developed an extensive myocardial infarction despite prompt treatment with streptokinase.
Coronary angiography revealed normal coronary arteries four weeks post-incident.

Findings:

The myocardial infarction is attributed to coronary artery spasm.
Contributing factors include systemic hypoxia, carbon dioxide (CO2) intoxication, and adrenergic response.
An unknown individual local factor is postulated to explain the specific spasm localization.

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Implications:

This case highlights a potential, albeit rare, association between environmental toxic gas exposure and acute coronary events.
It underscores the importance of considering environmental factors in the differential diagnosis of myocardial infarction, especially in unusual circumstances.
Further research into individual susceptibility and local factors influencing vasospasm is warranted.