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Updated: Mar 15, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019
Circulating Non-coding RNA as Biomarkers in Colorectal Cancer
Manuela Ferracin1, Laura Lupini2, Alessandra Mangolini2
1Department of Experimental, Diagnostic and Specialty Medicine - DIMES, University of Bologna, Bologna, Italy. manuela.ferracin@unibo.it.
Abstract:
Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs - detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.
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