Related Experiment Video
Updated: Mar 15, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
Preventing Poor Vocational Functioning in Psychosis Through Early Intervention.
Wenche Ten Velden Hegelstad1, Kolbjorn S Bronnick1, Helene Eidsmo Barder1
1Dr. Hegelstad, Prof. Dr. Bronnick, Dr. Joa, Prof. Dr. Johannessen, Dr. Langeveld, and Prof. Dr. Larsen are with the Regional Centre for Clinical Research in Psychosis, Psychiatric Division, Stavanger University Hospital, Stavanger, Norway (e-mail: wenchetenvelden@mac.com ). Prof. Dr. Bronnick, Dr. Joa, and Prof. Dr. Johannessen are also with the Faculty of Social Sciences, University of Stavanger, Stavanger, Norway. Prof. Dr. Larsen is also with the Institute of Clinical Medicine, University of Bergen, Bergen, Norway. Dr. Barder is with the Women and Children's Division, and Prof. Dr. Friis is with the Division of Mental Health and Addiction, Oslo University Hospital, Oslo. Prof. Dr. Friis is also with the Institute of Clinical Medicine, University of Oslo, Oslo, where Prof. Dr. Melle, Prof. Dr. Opjordsmoen, and Prof. Dr. Rossberg are affiliated. Prof. Dr. Melle, Prof. Dr. Opjordsmoen, and Prof. Dr. Rossberg are also with the Division of Mental Health and Addiction, Oslo University Hospital, Ullevål, Oslo, where Dr. Evensen is affiliated. Dr. Haahr and Prof. Dr. Simonsen are with the Faculty of Health and Medical Sciences, Institute for Clinical Medicine, University of Copenhagen, Smedegade, Roskilde, Denmark. They are also with the Psychiatric Research Unit, Psychiatry Region Zealand, Toftegade, Roskilde, Denmark. Prof. Dr. Rund is with the Department of Psychology, and Prof. Dr. Vaglum is with the Department of Behavioral Sciences in Medicine, University of Oslo, Oslo. Prof. Dr. Rund is also with the Vestre Viken Hospital Trust, Drammen, Norway. Dr. McGlashan is with the School of Medicine, Yale University, New Haven, Connecticut.
Early psychosis detection improves long-term vocational functioning by preventing negative symptoms. This leads to better employment and study outcomes for individuals diagnosed with psychosis.
Area of Science:
- Psychiatry and Mental Health
- Vocational Rehabilitation
- Clinical Psychology
Background:
- Early detection of psychosis is crucial for long-term patient outcomes.
- Negative symptoms significantly impact vocational functioning in individuals with psychosis.
- The relationship between early detection, symptom development, and vocational success requires further investigation.
Purpose of the Study:
- To test the hypothesis that early psychosis detection improves long-term vocational functioning.
- To examine if preventing negative symptom development mediates the link between early detection and vocational outcomes.
- To compare vocational functioning in early versus usual psychosis detection areas over ten years.
Main Methods:
- Longitudinal study design comparing two groups: early detection (N=141) and usual detection (N=140) of psychosis.
- Generalized estimating equations and mediation analysis were used to analyze data over ten years.
- Key variables included employment status, study participation, and negative symptom severity.
Main Results:
- Early psychosis detection was associated with lower negative symptom levels within the first five years.
- Lower negative symptoms in the early years mediated improved vocational outcomes at ten years.
- Patients in the early detection area showed higher rates of full-time employment or study compared to the usual detection area.
Conclusions:
- Early detection of psychosis facilitates vocational careers by mitigating negative symptom development.
- Timely intervention in psychosis appears to positively influence long-term employment and educational attainment.
- The findings underscore the importance of early detection strategies in improving functional recovery for individuals with psychosis.
Related Concept Videos
Psychosis: Goals of Pharmacotherapy
Psychological and Sociocultural Causes of Schizophrenia
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Psychosis and Antipsychotic Drugs: Overview
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Schizophrenia

