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Updated: Mar 15, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
The Diagnosis and Management of Early Deep Vein Thrombosis
Vivak Hansrani1, Mustafa Khanbhai2, Charles McCollum2
1Academic Surgery Unit, University Hospital of South Manchester NHS Trust, 2nd Floor, Education and Research Centre, M23 9LT, Manchester, UK. vivak.hansrani@manchester.ac.uk.
Insights
Diagnosing deep vein thrombosis (DVT) is challenging, leading to costly litigation. Current UK diagnostic pathways for DVT often fail to address the root cause of symptoms after diagnosis.
Area of Science:
- Medical Diagnostics
- Vascular Medicine
- Health Services Research
Background:
- Acute deep vein thrombosis (DVT) diagnosis and management present significant challenges, with frequent diagnostic errors.
- Litigation costs for the National Health Service (NHS) due to delayed DVT diagnosis and treatment are substantial.
- Clinical diagnosis of DVT is often unreliable, and many hospital-acquired DVTs are asymptomatic.
Purpose of the Study:
- To evaluate the effectiveness of current DVT diagnostic pathways in the UK.
- To identify limitations in existing DVT diagnostic and management strategies.
- To explore improvements for DVT diagnosis and treatment, addressing the root cause of symptoms.
Main Methods:
- Review of current DVT diagnostic pathways in the United Kingdom.
- Analysis of the utilization of clinical scoring systems, D-dimer assays, and ultrasound (US) imaging.
- Assessment of the efficacy of DVT pathways in excluding DVT versus addressing underlying causes.
Main Results:
- Current DVT diagnostic pathways in the UK rely on clinical scoring, D-dimer, and ultrasound.
- These pathways are primarily designed to exclude DVT, not to address the underlying causes of symptoms.
- A significant proportion of hospital-associated DVTs remain asymptomatic, complicating diagnosis.
Conclusions:
- Existing DVT diagnostic pathways require enhancement to move beyond simple exclusion.
- There is a need to develop strategies that address the etiological factors of DVT symptoms.
- Improving DVT diagnosis and management is crucial to reduce NHS litigation costs and improve patient outcomes.
Abstract:
The diagnosis and management of an acute DVT is difficult and mistakes are often made. The cost to the National Health Service (NHS) of litigation arising from failure to diagnose and treat DVT early is substantial. Clinical diagnosis alone is often unreliable and a large proportion of DVT occurring in hospital are asymptomatic. In the United Kingdom, clinical scoring systems, D-dimer and ultrasound (US) imaging have all been adopted to aid diagnosis via DVT pathways. These pathways aim to exclude DVT only and often fail to actually address the cause of the symptoms once DVT is eventually cleared.
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