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Related Concept Videos

Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Related Experiment Video

Updated: Mar 14, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

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A dedicated neonatal brain imaging system.

Emer J Hughes1, Tobias Winchman2, Francesco Padormo1

  • 1Centre for the Developing Brain, Perinatal Imaging and Health, Imaging Sciences and Biomedical Engineering Division, Kings College, London, United Kingdom.

Magnetic Resonance in Medicine
|September 20, 2016
PubMed
Summary
This summary is machine-generated.

A new neonatal brain imaging system (NBIS) significantly improves MRI signal-to-noise ratio and protocol completion rates in infants. This system enables advanced brain connectivity mapping in newborns without sedation.

Keywords:
brainhead coilneonatalunsedated

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Area of Science:

  • Neuroimaging
  • Medical Imaging

Background:

  • Developing Human Connectome Project aims to map neonatal brain connectivity.
  • Imaging 1000 neonates presents significant technical challenges due to lack of sedation.

Purpose of the Study:

  • To develop and evaluate a specialized neonatal brain imaging system (NBIS).
  • To overcome challenges in acquiring high-quality MRI in non-sedated neonates.

Main Methods:

  • Designed a dedicated 32-channel receive array coil and positioning device for neonates.
  • Utilized MRI-compatible transport, minimized acoustic noise, and implemented motion correction techniques.
  • Compared NBIS performance against an adult head coil for SNR, protocol completion, and motion artifacts.

Main Results:

  • NBIS achieved 2.4 times higher signal-to-noise ratio compared to an adult coil.
  • Demonstrated a 90% protocol completion rate in the neonatal cohort.
  • Reduced motion artifacts in anatomical images.

Conclusions:

  • NBIS facilitates advanced neonatal brain imaging with high success rates.
  • The system is crucial for the Developing Human Connectome Project's goals.
  • Enables high-quality, non-sedated MRI for early brain development studies.