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Polypharmacology in Precision Oncology: Current Applications and Future Prospects

Albert A Antolin1, Paul Workman, Jordi Mestres

  • 1Division of Cancer Therapeutics, The Institute of Cancer Research, London, United Kingdom.

Current Pharmaceutical Design
|September 28, 2016
PubMed
Summary

Drug polypharmacology offers new ways to fight cancer by targeting multiple pathways simultaneously. This approach can overcome drug resistance and enable drug repurposing for better precision oncology outcomes.

Keywords:
Polypharmacologybiomarkermulti-target drug design.off-targetprecision oncologyside-effectssystems pharmacologytarget profiling

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