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Gene Therapy and its Implications in Dentistry
A R Prabhakar1, Jibi M Paul2, N Basappa3
1Professor and Head, Department of Pedodontics and Preventive Dentistry, Bapuji Dental College and Hospital, Davangere, Karnataka, India.
International Journal of Clinical Pediatric Dentistry
|September 28, 2016
Summary
Gene therapy, involving gene transfer, is advancing rapidly, offering new treatment possibilities beyond severe diseases. This review explores its progress and dental applications.
Area of Science:
- Biotechnology
- Molecular Biology
- Genetics
Background:
- Gene therapy, the transfer of genes for clinical use, has evolved significantly over decades.
- Recombinant DNA technology has accelerated progress, expanding potential applications beyond life-threatening conditions.
- Gene therapy is increasingly considered for non-life-threatening diseases impacting quality of life due to limited conventional treatments.
Purpose of the Study:
- To review advancements in gene transfer strategies.
- To examine the application of gene therapy for diseases and conditions relevant to dental practice.
Main Methods:
- Review of scientific literature on gene transfer and therapy.
- Analysis of progress in addressing genetic diseases and dental conditions.
Main Results:
- Significant progress has been made in gene therapy techniques.
- Challenges remain for routine clinical application of gene transfer.
- Gene therapy shows promise for diverse biological science applications.
Conclusions:
- Gene therapy is poised to have a substantial impact across biological sciences.
- Further research is needed to overcome existing challenges for widespread clinical adoption.
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