Related Experiment Video
Updated: Mar 14, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
Published on: June 13, 2014
Opportunities for glyconanomaterials in personalized medicine
Niels-Christian Reichardt1, Manuel Martín-Lomas2, Soledad Penadés2
1CIC biomaGUNE, Glycotechnology Laboratory, Paseo Miramón 182, 20009 San Sebastian, Spain. nreichardt@cicbiomagune.es and CIBER BBN, Paseo Miramón 182, 20009 San Sebastian, Spain.
Abstract:
In this feature article we discuss the particular relevance of glycans as components or targets of functionalized nanoparticles (NPs) for potential applications in personalized medicine but we will not enter into descriptions for their preparation. For a more general view covering the preparation and applications of glyconanomaterials the reader is referred to a number of recent reviews. The combination of glyco- and nanotechnology is already providing promising new tools for more personalized solutions to diagnostics and therapy. Current applications relevant to personalized medicine include drug targeting, localized radiation therapy, imaging of glycan expression of cancer cells, point of care diagnostics, cancer vaccines, photodynamic therapy, biosensors, and glycoproteomics.
Related Concept Videos
Protein Glycosylation
Glycosylation occurs in...
Proteoglycans
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Microorganisms in Medicine and Therapeutics

