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Updated: Mar 13, 2026

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
Published on: September 6, 2012
Organic Polymer Chemistry in the Context of Novel Processes
Joseph M DeSimone1, Sue J Mecham2, Crista L Farrell2
1Chemistry Department, University of North Carolina, Chapel Hill, North Carolina 27599, United States; Chemical Engineering Department, North Carolina State University, Raleigh, North Carolina 27695, United States; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Abstract:
This article was written to shed light on a series of what some have stated are not so obvious connections that link polymer synthesis in supercritical CO2 to cancer treatment and vaccines, nonflammable polymer electrolytes for lithium ion batteries, and 3D printing. In telling this story, we also attempt to show the value of versatility in applying one's primary area of expertise to address pertinent questions in science and in society. In this Outlook, we attempted to identify key factors to enable a versatile and nimble research effort to take shape in an effort to influence diverse fields and have a tangible impact in the private sector through the translation of discoveries into the marketplace.
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