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Updated: Mar 13, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Validity and Reliability of the Filipino Reflux Symptom Index
José Florencio F Lapeña1, Giancarla Marie C Ambrocio2, Ryner Jose D Carrillo3
1Professor of Otorhinolaryngology and Attending Otorhinolaryngologist, College of Medicine-Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
The Filipino Reflux Symptom Index (FRSI) is a valid and reliable tool for assessing laryngopharyngeal reflux (LPR) symptoms in Filipino patients. It effectively tracks symptom improvement after a 6-month rabeprazole treatment.
Area of Science:
- Otolaryngology
- Gastroenterology
- Health Outcomes Research
Background:
- Laryngopharyngeal reflux (LPR) presents diagnostic challenges.
- Validated symptom assessment tools are crucial for LPR management, especially in diverse populations.
- The Filipino Reflux Symptom Index (FRSI) was developed to address this need.
Purpose of the Study:
- To establish the validity and reliability of the Filipino Reflux Symptom Index (FRSI).
- To evaluate the FRSI's effectiveness in tracking symptom changes in patients with LPR undergoing treatment.
- To assess the FRSI's utility as a screening tool in primary care settings.
Main Methods:
- A case-control study involving 35 LPR patients and 30 controls.
- Administration of the FRSI and Filipino Voice Handicap Index (FVHI) for reliability testing.
- Videostroboscopy and Reflux Finding Scores (RFS) were used for objective assessment.
- Patients received rabeprazole 20 mg twice daily for 6 months, with repeated assessments.
Main Results:
- The FRSI demonstrated good item-total correlations, indicating sound psychometric properties.
- Significant differences in FRSI scores were observed between LPR patients and controls.
- FRSI scores significantly decreased after 6 months of rabeprazole treatment, indicating symptom improvement.
- The FRSI showed greater sensitivity to treatment-induced changes compared to the FVHI.
Conclusions:
- The FRSI is a valid and reliable instrument for assessing LPR symptoms in Filipino individuals.
- The FRSI can be utilized for primary care screening of LPR.
- A positive response to a short proton pump inhibitor trial may suggest LPR, while non-response necessitates further specialist evaluation.
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