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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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Drug Hepatotoxicity: Newer Agents.

Chalermrat Bunchorntavakul1, K Rajender Reddy2

  • 1Division of Gastroenterology and Hepatology, Department of Medicine, University of Pennsylvania, 2 Dulles, 3400 Spruce Street, HUP, Philadelphia, PA 19104, USA; Division of Gastroenterology and Hepatology, Department of Medicine, Rajavithi Hospital, College of Medicine, Rangsit University, Rajavithi Road, Ratchathewi, Bangkok 10400, Thailand.

Clinics in Liver Disease
|November 16, 2016
PubMed
Summary

Newer medications, including tyrosine kinase inhibitors and monoclonal antibodies, show lower rates of drug-induced liver injury (DILI). However, severe liver damage cases still occur with some novel agents.

Keywords:
AntibioticsAnticoagulantsAntiplateletAntiretroviralsDrug-induced liver injuryHepatotoxicityMonoclonal antibodiesTyrosine kinase inhibitors

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