Spontaneous Regression of Choroidal Neovascularization in a Patient with Pattern Dystrophy

Area of Science:

• Ophthalmology
• Retinal Diseases

Background:

• Pattern dystrophy (PD) is a group of inherited retinal diseases.
• Choroidal neovascularization (CNV) can be a complication of various retinal conditions.
• CNV often requires treatment to prevent vision loss.

Purpose of the Study:

• To report a case of spontaneous resolution of CNV in a patient with PD.
• To evaluate the natural history of untreated CNV in this context.

Main Methods:

• A 69-year-old male with PD and recent visual loss underwent fundus examination, autofluorescence, and fluorescein angiography.
• Choroidal neovascularization (CNV) was identified in the left eye.
• The patient opted for observation due to satisfactory visual acuity, with follow-up at 6 and 12 months using OCT.

Main Results:

• Visual acuity remained stable at 0.9 (baseline BCVA) throughout the 12-month follow-up.
• Optical Coherence Tomography (OCT) revealed complete spontaneous regression of the choroidal neovascular membrane.
• No intra- or subretinal fluid was detected during follow-up visits.

Conclusions:

• Spontaneous regression of choroidal neovascularization (CNV) is possible in patients with pattern dystrophy (PD).
• The decision for observation versus treatment should consider presenting visual acuity.
• Isolated cases of spontaneous resolution of CNV can occur, impacting management strategies.