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Updated: Mar 11, 2026
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Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
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Breast Lumps That Do Not Arise from the Breast
Srinivas Kodaganur1, Priyadarshini C A1, Ishwar R Hosamani1
1Department of General Surgery, Karnataka Institute of Medical Sciences, HUBLI, India.
Indian Journal of Surgical Oncology
|November 23, 2016
Summary
A breast lump in an elderly woman was initially suspected to be a phylloides tumor. However, biopsy revealed adenocarcinoma cells, identical to those found in a rectal growth, highlighting a rare diagnostic challenge.
Area of Science:
- Oncology
- Surgical Pathology
- Gastroenterology
Background:
- Breast lumps are common in surgical outpatient settings, with phylloides tumors being a differential diagnosis.
- Rectal growths can present with varied symptoms, sometimes mimicking other conditions.
Purpose of the Study:
- To report a rare case of concurrent breast and rectal adenocarcinoma.
- To emphasize the importance of thorough clinical examination and histopathological correlation.
Main Methods:
- Clinical presentation of a large, hard, fixed breast mass.
- Digital rectal examination revealing a circumferential rectal growth.
- Histopathological analysis of biopsies from both the breast mass and rectal growth.
Main Results:
- Biopsy of the breast mass showed adenocarcinoma.
- Biopsy of the rectal growth also showed adenocarcinoma with similar cell morphology.
- The findings suggest a metastatic or synchronous primary adenocarcinoma in both locations.
Conclusions:
- Concurrent adenocarcinoma in the breast and rectum can occur, presenting a diagnostic challenge.
- This case underscores the necessity of comprehensive evaluation beyond initial diagnostic assumptions.
- Histopathological confirmation is crucial for accurate diagnosis and treatment planning in complex presentations.
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