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Updated: Mar 11, 2026
Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
Published on: May 2, 2025
Supratentorial Tumors in Pediatric Patients
Carlos Zamora1, Thierry A G M Huisman2, Izlem Izbudak3
1Section of Pediatric Neuroradiology, Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0842, USA; Division of Neuroradiology, Department of Radiology, University of North Carolina School of Medicine, 3326 Old Infirmary Road, Chapel Hill, NC 27514, USA.
Abstract:
The breadth of tumors that can arise in the supratentorial brain in children is extensive. With the exception of those that result in seizures and the highly malignant histologies, supratentorial tumors may come to medical attention later compared with infratentorial tumors, as they are less commonly associated with ventricular obstruction. This article presents an overview of the neuroimaging characteristics of these entities, with particular attention to relevant features that may aid in narrowing the differential diagnosis, including correlation with demographics and clinical presentation.
