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Updated: Mar 11, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Brain Tumors in the Neonate
Karuna V Shekdar1, Erin Simon Schwartz1
1The Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, # 2115 Wood building, 34 and Civic Center Boulevard, Philadelphia, PA 19146, USA.
Early detection of prenatal and neonatal brain tumors is vital. Neuroimaging aids in identifying tumor characteristics, hydrocephalus, and spread, guiding diagnosis and treatment.
Area of Science:
- Pediatric oncology
- Neuroradiology
- Fetal and neonatal medicine
Background:
- Brain tumors can manifest during the prenatal and neonatal periods.
- Early detection and characterization are critical for appropriate management.
- Neuroimaging plays a pivotal role in the diagnostic process.
Purpose of the Study:
- To highlight the importance of neuroimaging in detecting and characterizing prenatal and neonatal brain tumors.
- To describe the key imaging features of common neonatal brain tumors.
- To differentiate between true neoplasms and mimic conditions.
Main Methods:
- Review of neuroimaging studies in neonates with brain tumors.
- Analysis of imaging findings including morphology, hydrocephalus, invasion, and spread.
- Correlation of imaging features with specific tumor types.
Main Results:
- Neuroimaging enables detailed morphological assessment of brain tumors.
- Imaging can identify associated complications like hydrocephalus.
- Specific imaging patterns aid in the diagnosis of common neonatal tumors such as teratomas, choroid plexus tumors, and ATRTs, as well as neoplasm mimics.
Conclusions:
- Neuroimaging is indispensable for the early diagnosis and management of neonatal brain tumors.
- Understanding characteristic imaging features aids in differentiating various tumor types and mimics.
- Timely diagnosis through imaging impacts treatment strategies and patient outcomes.
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