Related Experiment Video
Updated: Mar 11, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Inflammatory Disorders of the Small Bowel
Jonathan A Leighton1, Shabana F Pasha1
1Division of Gastroenterology and Hepatology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA.
Diagnosing small bowel inflammation like Crohn disease requires advanced imaging. Techniques like capsule endoscopy and deep enteroscopy aid in diagnosis and treatment, with safety measures for capsule retention.
Area of Science:
- Gastroenterology
- Small Bowel Diseases
- Inflammatory Bowel Disease
Background:
- Common small bowel inflammatory disorders include Crohn disease, NSAID enteropathy, and celiac disease.
- Advanced imaging modalities play a crucial role in diagnosing and evaluating these conditions.
Purpose of the Study:
- To outline the roles of various endoscopic and imaging techniques in managing small bowel inflammatory disorders.
- To highlight methods for minimizing risks associated with capsule endoscopy.
Main Methods:
- Review of diagnostic and therapeutic roles of capsule endoscopy, CT enterography, MR enterography, and deep enteroscopy.
- Discussion of strategies to mitigate capsule retention risks in patients with Crohn disease and NSAID enteropathy.
Main Results:
- Capsule endoscopy, CTE, and MRE are complementary for Crohn disease diagnosis and evaluation.
- Cross-sectional imaging or patency capsules can reduce the risk of capsule retention.
- Deep enteroscopy is essential for tissue diagnosis, endoscopic management of lesions/strictures, and capsule retrieval.
Conclusions:
- A combination of advanced imaging and endoscopic techniques is vital for comprehensive small bowel disorder management.
- Risk mitigation strategies are important for safe application of capsule endoscopy.
Related Concept Videos
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Other Disorders of Digestive System
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

