Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anodal high-definition transcranial direct current stimulation reveals a specific role for posterior parietal cortex in interlimb generalization.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same author

The phenprocoumon echo: Elevated INR risk after VKA reversal - A retrospective analysis of phenprocoumon and acenocoumarol in clinical practice in a Dutch teaching hospital.

European journal of clinical pharmacology·2026
Same author

Differential brain reorganization in chronic cervical spinal cord injury and its relation to motor versus sensory impairments: a preliminary investigation.

Scientific reports·2026
Same author

The influence of hand dominance, object distance, and size on reach-to-grasp coordination in a virtual environment.

Experimental brain research·2026
Same author

Source-Level Resting-State EEG Connectivity Reveals Frequency-Specific Neural Reorganization and Predicts Motor Recovery in Individuals Post Stroke Following Gait Rehabilitation.

Research square·2026
Same author

Robust neural network controller for a lower limb exoskeleton with minimal sensor configuration: a deep reinforcement learning approach with policy distillation.

Journal of neuroengineering and rehabilitation·2025
Same journal

Decoding functional changes in the brain following ischemic stroke: a multimodal feature approach integrating fNIRS with machine learning and deep learning.

NeuroImage. Clinical·2026
Same journal

Structural brain alterations in chronic primary pain: a multimodal MRI study.

NeuroImage. Clinical·2026
Same journal

Using functional MRI neurofeedback to modulate self-blame in major depressive disorder: A pilot study.

NeuroImage. Clinical·2026
Same journal

Language network reorganization in temporal lobe epilepsy: insights from task-based functional MRI.

NeuroImage. Clinical·2026
Same journal

Functional brain biomarkers of self-referential bias in remitted depressed outpatients: a randomized controlled trial.

NeuroImage. Clinical·2026
Same journal

Stress-related hypofrontality in depression and its relation to altered activation prior to the stress response.

NeuroImage. Clinical·2026
See all related articles

Related Experiment Video

Updated: Mar 10, 2026

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.6K

Network interactions underlying mirror feedback in stroke: A dynamic causal modeling study.

Soha Saleh1, Mathew Yarossi2, Thushini Manuweera2

  • 1Human Performance and Engineering Lab, Kessler Foundation, 1199 Pleasant Valley Way, West Orange, NJ 07052, United States.

Neuroimage. Clinical
|December 7, 2016
PubMed
Summary
This summary is machine-generated.

Mirror visual feedback (MVF) activates the ipsilesional motor cortex via the contralesional parietal lobe in stroke patients. This suggests an action observation network, not direct motor cortex transfer, underlies MVF

Keywords:
DCMMirror feedbackMotor controlVirtual realityVisuomotor integrationfMRI

More Related Videos

Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms
10:32

Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms

Published on: August 15, 2016

16.1K
Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
11:29

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain

Published on: April 20, 2019

10.4K

Related Experiment Videos

Last Updated: Mar 10, 2026

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.6K
Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms
10:32

Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms

Published on: August 15, 2016

16.1K
Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
11:29

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain

Published on: April 20, 2019

10.4K

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Cognitive Neuroscience

Background:

  • Mirror visual feedback (MVF) shows promise for motor recovery and brain activation after stroke.
  • The precise neural network interactions driving MVF's effects on sensorimotor areas remain unclear.
  • Understanding these mechanisms is crucial for optimizing stroke rehabilitation strategies.

Purpose of the Study:

  • To investigate the network interactions modulating ipsilesional motor cortex activation during MVF in stroke patients.
  • To differentiate between direct interhemispheric motor cortex transfer and action observation network recruitment.
  • To identify specific brain regions involved in processing mirror feedback.

Main Methods:

  • Used functional magnetic resonance imaging (fMRI) with dynamic causal modeling in 14 chronic stroke subjects.
  • Subjects performed goal-directed finger movements with their unaffected hand while observing real or mirror visual feedback.
  • Tested 30 plausible network models to determine the most likely neural interactions.

Main Results:

  • The most supported model indicated that mirror visual feedback modulated the ipsilesional motor cortex through the contralesional parietal cortex (rostral intraparietal sulcus).
  • This effect was specific to mirror feedback; no significant network model was found for veridical feedback.
  • Findings support the role of the action observation network in mediating MVF effects.

Conclusions:

  • Mirror visual feedback-induced motor cortex activation in stroke is likely mediated by the contralateral action observation network.
  • The contralesional parietal cortex plays a key role in this process.
  • These findings may guide the use of non-invasive brain stimulation to enhance mirror therapy outcomes.