A computerized respiratory system including test functions of lung and circulation

Area of Science:

• Biomedical Engineering
• Respiratory Physiology
• Animal Research

Background:

• Mechanical ventilators are crucial for respiratory support and physiological studies.
• Existing systems may lack the flexibility for complex experimental protocols.
• Paralyzed animal models require precise ventilation control for accurate data acquisition.

Purpose of the Study:

• To describe the design and capabilities of a microcomputer-controlled ventilator.
• To enable automatic performance of lung function and circulatory tests.
• To provide a versatile platform for physiological research in animal models.

Main Methods:

• The system integrates a pump assembly with solenoid valves, an electromechanical servo system, and an MS-DOS microcomputer.
• Software allows for adaptable control of respiratory parameters and remote operation.
• The design facilitates closed-loop servo ventilation and automatic experimental protocols.

Main Results:

• The microcomputer control offers significant versatility and adaptability for various experimental needs.
• The ventilator successfully mimics normal mechanical ventilation and supports diverse test procedures.
• It has been effectively utilized in multiple animal studies over the past six years.

Conclusions:

• The developed microcomputer-controlled ventilator is a flexible and powerful tool for lung function and circulatory research.
• Its adaptable software and control features make it suitable for a wide range of experimental applications.
• The system enhances the ability to conduct complex physiological studies in paralyzed animals.