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Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
Published on: October 17, 2018
Transient myocarditis associated with acute Zika virus infection
M Aletti1, S Lecoules1, V Kanczuga2
1Department of Internal Medicine, Percy Military Teaching Hospital, Clamart, France.
The Zika virus outbreak has reached America, causing neurological issues. This report details the first case of Zika-induced myocarditis in France, emphasizing cardiac monitoring for infected patients.
Area of Science:
- Infectious Diseases
- Cardiology
- Neurology
Background:
- The Zika virus outbreak is a growing global health concern.
- Zika virus infection is known to cause neurological complications.
- Cardiac involvement in Zika virus infection is less understood.
Purpose of the Study:
- To report the first case of travel-acquired Zika virus infection complicated by myocarditis in Mainland France.
- To highlight the potential for cardiac complications in Zika virus cases.
- To recommend diagnostic approaches for cardiac involvement in acute Zika infection.
Main Methods:
- Case report of a patient with travel-acquired Zika virus infection.
- Clinical assessment including cardiac symptom evaluation.
- Diagnostic workup including electrocardiogram and troponin levels.
Main Results:
- The patient presented with acute Zika virus infection.
- The infection was complicated by myocarditis, a rare cardiac manifestation.
- Electrocardiogram and troponin levels were key in diagnosing cardiac involvement.
Conclusions:
- Zika virus infection can lead to myocarditis, even in travel-acquired cases.
- Cardiac monitoring, including electrocardiogram and troponin, is recommended for patients with acute Zika infection exhibiting cardiac symptoms.
- This case underscores the importance of considering cardiac complications in the differential diagnosis of febrile illnesses with potential Zika virus exposure.
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