Modification of the deoxyribose test to detect strong iron binding

Deoxyribose test has been widely used for determination of reactivities of various compounds for the hydroxyl radical. The test is based on the formation of hydroxyl radical by Fe²⁺ complex in the Fenton reaction. We propose a modification of the deoxyribose test to detect strong iron binding, inhibiting participation of Fe²⁺ in the Fenton reaction, on the basis of examination of concentration dependence of deoxyribose degradation on Fe²⁺ concentration, at a constant concentration of a chelating agent.