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Idiopathic Multifocal Choroiditis.

Ali Tavallali¹, Lawrence A Yannuzzi¹

¹Vitreous-Retina-Macula Consultants of New York, New York, USA; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Institute, New York, USA; Edward S. Harkness Eye Institute, Columbia University, New York, USA.

Journal of Ophthalmic & Vision Research

|December 21, 2016

Summary

This summary is machine-generated.

Idiopathic multifocal choroiditis (MFC) and punctate inner choroidopathy (PIC) are chronic inflammatory eye conditions primarily affecting healthy women. Treatment focuses on controlling inflammation and preventing complications like choroidal neovascularization (CNV).

Keywords:

Idiopathic Multifocal Choroiditis Panuveitis Punctate Inner Choroidopathy

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Area of Science:

Ophthalmology
Inflammatory eye diseases

Background:

Idiopathic multifocal choroiditis (MFC) and punctate inner choroidopathy (PIC) are chronic, progressive, bilateral inflammatory chorioretinopathies.
These conditions predominantly affect healthy, myopic white women, with no known associated systemic or ocular diseases.

Approach:

The primary sites of involvement are the retinal pigment epithelium (RPE) and outer retinal spaces.
The choroid is typically not affected during the active phase of the disease.

Key Points:

Idiopathic MFC with atrophy is a recently described variant.
Current treatment strategies are not standardized but often involve anti-inflammatory agents and anti-VEGF (vascular endothelial growth factor) therapies.
These agents are crucial in the acute stage for managing inflammation and choroidal neovascularization (CNV).

Conclusions:

MFC and PIC represent significant inflammatory chorioretinopathies requiring management of acute inflammation and potential complications.
Further research into standardized treatments for these conditions is warranted.