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PREDICTORS FOR POST- STROKE DELIRIUM OUTCOME.

Zikrija Dostovic1, Ernestina Dostovic2, Dzevdet Smajlovic1

  • 1Department of Neurology, University Clinical Centre Tuzla, Bosnia and Herzegovina.

Materia Socio-Medica
|December 22, 2016
PubMed
Summary
This summary is machine-generated.

Post-stroke delirium significantly impacts patient outcomes and survival. Advanced age and medical complications are key predictors of poor prognosis, with delirium causing lasting cognitive impairment.

Keywords:
deliriumoutcomepredictorsstroke

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Area of Science:

  • Neurology
  • Geriatrics
  • Psychiatry

Background:

  • Limited research exists on the outcomes of post-stroke delirium.
  • Understanding factors influencing post-stroke delirium is crucial for patient management.

Purpose of the Study:

  • To investigate the influence of various factors (gender, age, stroke localization, delirium severity, comorbidities, complications) on post-stroke delirium outcomes.
  • To assess the long-term effects of delirium on cognitive function one year post-stroke.

Main Methods:

  • Utilized comprehensive neuropsychological assessments at multiple time points (1 week, discharge, 3, 6, 12 months).
  • Employed diagnostic tools including the Glasgow Coma Scale, Delirium Rating Scale, National Institutes of Health Stroke Scale, and Mini-Mental State examination.

Main Results:

  • Patients with post-stroke delirium experienced significantly more medical complications (p=0.0005).
  • Age (≥65 years) was the strongest predictor of mortality (OR 4.9).
  • Medical complications were the strongest predictor of poor outcome (Hazard-risk 3.3).
  • Delirium patients showed significant cognitive impairment at 3, 6, and 12 months post-stroke (p=0.0005).

Conclusions:

  • Patient gender, age, stroke localization, delirium severity, chronic diseases, and complications significantly influence post-stroke delirium outcomes.
  • Post-stroke delirium leads to substantial and persistent cognitive deficits.