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Aptamer-tagged DNA origami for spatially addressable detection of aflatoxin B1

Zhisong Lu1, Ying Wang1, Dan Xu2

  • 1Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, P. R. China and Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, 1 Tiansheng Road, Chongqing 400715, P. R. China. zslu@swu.edu.cn.

Chemical Communications (Cambridge, England)
|December 24, 2016
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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