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Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain

Haiming Huang1,2, Tomonori Kaneko3, Sachdev S Sidhu4,5

  • 1Banting and Best Department of Medical Research, University of Toronto, Donnelly Centre, 160 College Street, Toronto, ON, Canada, M5S 3E1.

Methods in Molecular Biology (Clifton, N.J.)
|January 17, 2017
PubMed

Keywords:
Directed evolutionModular domainPhage displayPhosphotyrosinePost-translational modificationSrc homology 2 (SH2) domain

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