ISCEV Standard for clinical electro-oculography (2017 update).

Area of Science:

• Ophthalmology
• Electrophysiology
• Visual Science

Background:

• The clinical electro-oculogram (EOG) assesses outer retinal function.
• It measures electrical potential changes across the retinal pigment epithelium (RPE) during light and dark adaptation.
• The International Society for Clinical Electrophysiology of Vision (ISCEV) previously published EOG standards in 2011.

Purpose of the Study:

• To present the updated 2017 ISCEV EOG Standard.
• To provide reorganized and updated guidance on EOG testing protocols.
• To promote consistent quality in EOG testing and reporting across clinical centers.

Main Methods:

• The standard details methods for recording the EOG in clinical settings.
• It provides guidance on technical requirements, practical considerations, and results reporting.
• The primary clinical measure, the Arden ratio, is now termed the light peak:dark trough ratio.

Main Results:

• The 2017 standard includes an explanation of the EOG mechanism.
• Substantive changes to the testing protocol compared to the 2011 version were avoided.
• The updated standard aims for consistency in clinical electrophysiology.

Conclusions:

• The 2017 ISCEV EOG Standard provides updated guidance for consistent electrophysiological assessment of the outer retina and RPE.
• Standardized testing and reporting are crucial for reliable clinical electrophysiology.
• This standard facilitates inter-center comparability in EOG measurements.