Related Experiment Video
Updated: Mar 8, 2026

An Experimental Model of Myocardial Infarction for Studying Cardiac Repair and Remodeling in Knockout Mice
Published on: July 14, 2023
[GALECTIN-3 LEVEL IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND OBESITY OF DIFFERENT GRADE OF SEVERITY: LINK WITH
K Borovyk1, N Ryndina1, P Kravchun1
1Kharkiv National Medical University, Department of Internal Medicine №2 and Clinical Immunology and Allergology, Ukraine.
Abstract:
The im is to estimate the concentration of galectin-3 in patients with acute myocardial infarction depending on the presence of overweight and obesity of different severity, as well as to analyze the character of the relationship of this parameter with the anthropometric indices. The study involved 78 patients with acute myocardial infarction. The study group included 55 patients with acute myocardial infarction and concomitant obesity. The control group consisted of 23 patients with acute myocardial infarction and normal body weight. Patients of the main group were divided according to the degree of severity of obesity. Obesity of I degree was detected in 26 individuals, II-III degrees - in 17 persons. Overweight was defined in 12 patients. It has been established that the presence and progression of obesity in patients with acute myocardial infarction accompanied by hyperactivity of pro-inflammatory mediator galectin-3, peaking in obese II-III degrees provided abdominal type of fat distribution. Overweight in turn, was not associated with a marked increased of galectin-3 production compared to those with normal weight.
More Related Videos
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Coronary Artery Disease III: Clinical Manifestations
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

