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Published on: August 4, 2009
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A highly sensitive and selective fluorescence off-on probe for the detection of intracellular endogenous tyrosinase
Xiaofeng Wu1, Xiaohua Li1, Hongyu Li2
1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. lixh@iccas.ac.cn mahm@iccas.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
A resorufin-based highly sensitive and selective fluorescence off-on probe with a new recognition moiety for tyrosinase is developed, and applied to detect and image endogenous tyrosinase activity in different living cells.

