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Updated: Mar 7, 2026

A Multimodal Wide-Field Fourier-Transform Raman Microscope
Published on: December 30, 2025
Multifrequency reconstruction for frequency-modulated bSSFP
Anne Slawig1, Tobias Wech1, Valentin Ratz1
1Department of Diagnostic and Interventional Radiology, University of Würzburg, Würzburg, Germany.
Purpose:
Banding artifacts in images acquired by balanced steady-state free precession (bSSFP) remain a challenge in MRI as they considerably reduce image quality, and diagnostic value deteriorates accordingly. As the steady-state tolerates small shifts in frequency, it is possible to acquire frequency-modulated bSSFP. Unfortunately, standard reconstructions of such measurements suffer from signal loss. Our study proposes a multifrequency reconstruction and demonstrates its capability of suppressing banding artifacts while retaining the high signal level of standard bSSFP.
Methods:
Numerical simulations in vitro and in vivo measurements were performed using both standard bSSFP and frequency-modulated bSSFP. The modulated data were reconstructed using a multifrequency approach consisting of three steps: phase correction, multiple reconstructions for different assumed frequencies, and maximum intensity projection.
Results:
Although standard bSSFP measurements showed banding artifacts that compromised the image quality, standard reconstructions of frequency-modulated acquisitions suffered from signal loss. In contrast, images reconstructed from frequency-modulated data using the proposed multifrequency reconstruction showed no visual bandings and featured a higher signal-to-noise ratio (SNR). The SNR gain for phantom and in vivo measurements ranged from 1.23 to 1.49.
Conclusions:
The presented multifrequency reconstruction for frequency-modulated bSSFP provides images showing no bandings and featuring high SNR in short scan times. Magn Reson Med 78:2226-2235, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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