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Published on: February 23, 2014
[Risk factors for poor prognosis in children with severe adenovirus pneumonia]
Miao Huang1, Rong Luo, Zhou Fu
1Deparment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. luo_rong_512@aliyun.com.
Objective:
To investigate the risk factors for poor prognosis of severe adenovirus pneumonia (SAP) in children.
Methods:
The clinical data of 189 children with SAP were retrospectively analyzed. Univariate logistic regression analysis was performed to assess the risk factors for poor prognosis.
Results:
The univariate logistic regression analysis showed that the patients with hemoglobin <90 g/L, plasma albumin <30 g/L, C-reactive protein >30 mg/L, procalcitonin >10 ng/mL, alanine aminotransferase >100 U/L, or aspartate aminotransferase >100 U/L had poor prognosis (P<0.05), and that those with congenital dysplasia of the airway, acute respiratory distress syndrome, circulatory complications, electrolyte and acid-base disturbance, or more than three complications also had poor prognosis (P<0.05).
Conclusions:
Poor prognosis of severe adenovirus pneumonia in children is associated with anemia, low serum albumin, inflammatory response, concurrent multiple complications and underlying lung diseases.
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