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Analgesic Effect of Xenon in Rat Model of Inflammatory Pain
M L Kukushkin1,2, S I Igon'kina3, S V Potapov3
1Research Institute of General Pathology and Pathological Physiology, Moscow, Russia. mkuk57@gmail.com.
Bulletin of Experimental Biology and Medicine
|March 1, 2017
Abstract:
The analgesic effects of inert gas xenon were examined on rats. The formalin model of inflammatory pain, tail-flick test, and hot-plate test revealed the antinociceptive effects of subanesthetizing doses of inhalation anesthetic xenon. Inhalation of 50/50 xenon/oxygen mixture moderated the nociceptive responses during acute and tonic phases of inflammatory pain.
