Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

1.9K
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
1.9K
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

525
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
525
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

718
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
718
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

367
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
367
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

968
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
968
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

538
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
538

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case report: neuroimaging in Cockayne syndrome.

Radiology case reports·2025
Same author

Angiographic Characteristics and Associated Risk Factors of Premature Coronary Artery Disease among South Asians: A Systematic Review.

The American journal of cardiology·2025
Same author

Comprehensive analysis of heavy metal contamination in the Mandakini (Payaswini) river: Multivariate and index-based perspectives.

Water environment research : a research publication of the Water Environment Federation·2025
Same author

Rural-urban disparity in survival and use of PCI in patients who develop STEMI while hospitalized for a non-cardiac condition.

Current problems in cardiology·2025
Same author

Navigating the Nexus: Acute Kidney Injury in Acute Stroke - A Prospective Cohort Study.

Annals of Indian Academy of Neurology·2024
Same author

Rare Case of Neuroendocrine Metastasis to the Left Ventricle.

JACC. Case reports·2024
Same journal

Lyme Carditis and Inflammation-Driven Plaque Erosion Presenting as Sudden Cardiac Arrest.

Texas Heart Institute journal·2025
Same journal

Risk Factors for Development of Stroke in Patients With Continuous-Flow Left Ventricular Assist Device Support as Destination Therapy.

Texas Heart Institute journal·2025
Same journal

Midterm Outcomes of Pediatric Mitral Valvuloplasty for Moderate to Severe Mitral Valve Regurgitation and Associated Risk Factors for Postoperative Deterioration.

Texas Heart Institute journal·2025
Same journal

Navigating the Complexities of Mitral Valve Clipping: Early Severe Mitral Valve Stenosis After Mitral Valve Clipping.

Texas Heart Institute journal·2025
Same journal

The Department of Cardiovascular Anesthesia of The Texas Heart Institute: An Informal History.

Texas Heart Institute journal·2025
Same journal

Contributions of Pathobiological and Translational Science to Understanding and Managing Ischemic Heart Disease: Progress, Impediments, and Future Directions.

Texas Heart Institute journal·2025
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

668

Transcatheter Aortic Valve Replacement: Comprehensive Review and Present Status.

Sameer Arora, Jacob A Misenheimer, Radhakrishnan Ramaraj

    Texas Heart Institute Journal
    |March 8, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Transcatheter aortic valve replacement offers a less invasive option for severe aortic stenosis, particularly for elderly patients deemed high-risk for traditional surgery. Newer valves show promise for improved outcomes and safety.

    Keywords:
    Age factorsaortic valve insufficiency/therapyaortic valve stenosis/mortality/surgeryevaluation studies as topicheart valve diseases/therapyheart valve prosthesis implantation/adverse effects/instrumentationpostoperative complications/prevention & controlprosthesis design/trendstranscatheter aortic valve replacement/mortality/trendstreatment outcome

    More Related Videos

    Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
    09:57

    Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

    Published on: January 20, 2022

    3.2K
    Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
    05:31

    Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

    Published on: June 8, 2022

    3.5K

    Related Experiment Videos

    Last Updated: Mar 6, 2026

    Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
    06:04

    Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

    Published on: August 8, 2025

    668
    Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
    09:57

    Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

    Published on: January 20, 2022

    3.2K
    Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
    05:31

    Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

    Published on: June 8, 2022

    3.5K

    Area of Science:

    • Cardiology
    • Cardiovascular Surgery
    • Interventional Cardiology

    Background:

    • Aortic stenosis is the most prevalent valvular heart disease in developed nations, affecting approximately 7% of individuals over 65.
    • Severe symptomatic aortic stenosis carries a poor prognosis without intervention, yet many elderly patients are not referred for valve replacement due to surgical risks.

    Observation:

    • Transcatheter aortic valve replacement (TAVR) has emerged as a less invasive alternative to surgical aortic valve replacement.
    • Key trials like PARTNER and CoreValve US Pivotal have established TAVR as a preferred option for high-risk patients.
    • The PARTNER 2 trial demonstrated TAVR's feasibility in intermediate-risk surgical patients.

    Findings:

    • TAVR is now a viable and preferred treatment for severe aortic stenosis in high-risk and, increasingly, intermediate-risk surgical patients.
    • Advancements in newer-generation TAVR devices suggest potential for enhanced valve performance, delivery, and improved patient outcomes.
    • The adoption of TAVR addresses the unmet need for less invasive treatment options in a growing elderly population with aortic stenosis.

    Implications:

    • TAVR represents a significant advancement in managing aortic stenosis, expanding treatment options for a vulnerable patient population.
    • Continued innovation in TAVR technology is expected to further improve safety profiles and long-term results.
    • This minimally invasive approach may redefine the standard of care for aortic stenosis, especially in elderly and frail individuals.