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Updated: Mar 5, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
[Epidemiology of strokes in pediatry]
Yannick Béjot1, Benoit Delpont1, Christelle Blanc1
1Registre Dijonnais des AVC, CHU Dijon Bourgogne, 14 rue Gaffarel, 21089 Dijon, France.
Insights
Perinatal arterial stroke affects 20-65 per 100,000 births, while childhood stroke impacts 1.3-4.3 per 100,000 annually. In France, nearly 450 children are hospitalized for stroke yearly, with half experiencing intracerebral hemorrhage.
Area of Science:
- Pediatric Neurology
- Vascular Neurology
- Public Health Epidemiology
Background:
- Perinatal arterial stroke is a significant concern, affecting newborns.
- Childhood stroke incidence requires further epidemiological understanding.
- Cerebral hemorrhage is a common stroke type in hospitalized children.
Purpose of the Study:
- To determine the incidence of perinatal arterial stroke.
- To establish the incidence of stroke in older children (29 days to 18 years).
- To quantify the burden of childhood stroke in France, specifically focusing on stroke types.
Main Methods:
- Retrospective epidemiological analysis of stroke incidence in neonates and children.
- Data collection on hospitalizations for stroke in children.
- Classification of stroke types, including ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage.
Main Results:
- Perinatal arterial stroke incidence ranges from 20 to 65 cases per 100,000 live births.
- Childhood stroke incidence (29 days to 18 years) is 1.3 to 4.3 per 100,000 per year.
- Approximately 450 children are hospitalized annually in France for stroke, with nearly half suffering intracerebral hemorrhage.
Conclusions:
- Perinatal arterial stroke and childhood stroke represent significant pediatric health issues.
- Intracerebral hemorrhage is a predominant subtype of stroke in hospitalized children.
- These findings highlight the need for continued research and preventative strategies for pediatric stroke.
Abstract:
Incidence of perinatal arterial stroke (ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage) occurring between 20 weeks of gestation and postnatal day 28 ranges between 20 and 65 cases per 100,000 living births. In children aged 29 days to 18 years old, the total incidence is 1.3 to 4.3 for 100,000 per year. In France, almost 450 children are hospitalized for a stroke each year, among them approximately half have an intracerebral hemorrhage.
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